hep c life expectancy

What is the prognosis and life expectancy of hepatitis C patient? - Premier Medical Labs | Official Site | Reference LaboratoryWhat is the expectation of Outlook and Life for Hepatitis C?Many people live with hepatitis C virus (HV) without knowing they have it. Hepatitis C, caused by HV, damages the liver. Some people with the virus make it clear without treatment. This is called acute hepatitis C. It is rarely associated with threatening living conditions. Read more about the latest treatments and prospects for hepatitis C. Complications of untreated hepatitis C, including cirrhosis (liver cancer) and liver cancer, may be fatal, although HCV itself is rarely fatal. According to the Centers for Disease Control and Prevention (CDC), people who develop CHC cirrhosis have the possibility of developing liver cancer, and the possibility of developing cirrhosis within 20 years. Hepatic decompensation (deterior in liver function) and liver failure are also possible complications. Perspective and life expectancy of people with chronic hepatitis C depend on the amount of their damaged liver. It also depends on how well a person responds to treatment. But the treatments have advanced a lot in recent years. Prospects are often optimistic, especially with early intervention. CDC estimates that people with HCV infection will develop chronic hepatitis C. Chronic hepatitis C is long-term and can lead to permanent cirrhosis or liver cancer. Chronic hepatitis C usually has no symptoms. People with chronic hepatitis C may not even know they have it. But once the symptoms appear, it means that the damage to the liver has already begun. Chronic hepatitis C treatment is often treatable. It usually involves taking a combination of medicines to reduce viral load to undetectable levels. These drugs work to prevent the virus from multiplying and eventually kill the virus. Drug regimens for hepatitis C is always changing and improving. Talk to your doctor about the latest treatments to see if they can work for you. After treatment, your doctor will make sure the virus is gone. Being clear of the virus, also called sustained virological response (SVR), means it will probably not return. But reinfection is still possible. In the United States, older drug regimes included interferon and ribavirin injection, an oral medication. Now, new oral medications called direct action antivirals (ADA) can be more effective and tolerated better. More cases can be cured with 8 to 12 weeks of therapy. This depends on:It is important to include routine HCV detection for certain populations to identify the infection before serious damage occurs. A delayed diagnosis can affect the effectiveness of treatment. GenotypeTreatment success for chronic hepatitis C also depends on the virus genotype. Genotypes are variations of the virus that have evolved over the years. Some genotypes can be more difficult to treat than others. Currently, 1a, 1b, 2, and 3 genotypes are HCV genotypes in the United States. Hepatitis C Cases in the United StatesThe CDC reports that in 2018, a total of U.S. death certificates had hepatitis C as an underlying cause or contributing to death. This is probably lower than real numbers, as many infections pass undocumented. Studies show that baby boomers (born between 1946 and 1964) are more likely than other groups to have been exposed to HCV. Most of them contracted infections during a peak of new infections. And since people with a HCV infection cannot show symptoms, they can transmit the virus to others without knowing it. Today, the most common risk factor for hepatitis C in the United States is injecting drug use. Since a VH infection cannot show symptoms, it is likely that the number of new cases is greater than the reported, according to the CDC. Hepatitis C can lead to cirrhosis, especially if not treated. Without treatment, cirrhosis can cause liver cancer and liver failure. Treating cirrhosis and liver cancer usually requires a liver transplant. A transplant can cure both cancer and impairment of liver function. But a transplant is only available for a small number of people. A of the impact of interferon therapy on HCV-related cancers concluded that the treatment is beneficial in the perspective of the disease. In June 2016, the Food and Drug Administration (FDA) the combined Epclusa medication (sofosbuvir/velpatasvir). This is the first medication approved to treat six hepatitis C genotypes. Treatment options and new drug regimens for hepatitis C are rapidly evolving. In 2019, FDA antiviral medication Mavyret (glecaprevir/pibrentasvir) for an 8-week treatment period for all genotypes. This was 4 weeks shorter than most other treatments with similar results. Instead of liver biopsies, newer imaging tests, magnetic resonance imaging (MRE) and transient elastography are being used to measure liver stiffness to determine the magnitude of the damage. Vaccines Since 2020, they are still working on a vaccine. There is currently no vaccination for hepatitis C. The virus is unique because it has at least seven different forms and . This immunological variability and challenges are obstacles to the success of the vaccine. The perspective of hepatitis C depends on the type of virus that causes it. In many cases, people may not know that they have acute hepatitis C, which around the clears alone. But for chronic hepatitis C, the perspective depends on a person's overall health, the degree of liver damage, the speed with which treatment is received and the response to treatment. Drug therapies for chronic hepatitis C can clean the virus, and newer therapies are often improving the success rates of these treatments. In general, prospects improve with early diagnosis. Symptoms or without symptoms? Chronic hepatitis C usually has no symptoms. People with chronic hepatitis C may not even know they have it. But once the symptoms appear, it means that the damage to the liver has already begun. Last medical review on August 28, 2020Read more here

What can I expect with time with hepatitis C? Very understandably, almost everyone diagnosed with hepatitis C virus asks the same question: "What's going to happen to me?" Unfortunately, with HCV infection, it is very difficult for doctors to provide an answer. More than with most diseases, the course of HCV infection varies widely from person to person. In about 15 to 25 percent of people infected with the virus, their immune systems attack the virus and remove it, and they never know they were exposed. At the other end there are people who develop chronic infections and eventually severe liver diseases. Among people who carry the virus, but never show signs of problems, and others who have mild symptoms and some liver damage, but never develop a serious disease. Many factors affect the course of HCV infection Many factors affect the course of HCV infection How can a virus act so differently in different people? Researchers don't know all the answers. They know that men are more likely to develop serious liver problems than women. A published study found that between 13 and 46 percent of men developed cirrhosis (carreo of the liver) for a 30-year period of being infected with VHC. Only 1 to 29 percent of women developed the disease during the same period. Age when infection occurs also makes a difference in the course of the disease. The former in life people are infected, the lower the risk of severe complications of hepatitis C infection. Other health problems and HCVO infection problems and HCV infectionInfections with other viruses may worsen the VH prognosis. Many people are infected with hepatitis C and HIV/AIDS. Both viruses spread through shared needles. In a large European study, 33% of HIV-positive patients were also infected with HPV. When experts looked at known injecting drug users, they found that 75% of HIV positive patients also had hepatitis C viruses. Being infected with these two viruses seems to increase the risk of cirrhosis. In 2008, researchers found that after 20 years of infection, the risk of developing cirrhosis was 21 percent in people who were both HCV and HIV and 16 percent for those infected with HCV only. Certain lifestyle aspects also shape the course of HCV infection. Infected and alcohol-consuming people are more likely to develop liver problems than nondrinkers. Alcoholics have the greatest risk. A study conducted by researchers at the University of Pennsylvania found that alcohol really causes hepatitis C virus to multiply faster. Alcohol also decreases the effectiveness of alpha interferon, which is used to treat severe HV infections. In a report, Italian researchers showed that alcohol increases oxidative stress in the liver, generating unstable free radicals that can damage liver cells. Scientists speculate that "oxidative injury can be one of the mechanisms by which alcohol contributes to the progression of chronic hepatitis C." Other researchers have found a connection between hepatitis C infection and diabetes and type 2 obesity. In 2009, scientists at the Inova Fairfax Hospital Center for Liver Diseases analyzed health data for nearly 16,000 people, including some with hepatitis C. According to the results of the study, obesity and type 2 diabetes were associated with a higher mortality rate in patients with hepatitis C. This finding suggests that making lifestyle changes to avoid obesity and diabetes should be an important consideration for people with hepatitis C. Surprisingly, the level of virus in the blood, called viral load, does not help predict the course of hepatitis C. Some people with high viral levels do well. Others, with low levels of viruses, develop liver problems. Doctors use the test to measure how well the treatment is working, but not to make a prognosis. High levels of aminotransferase, a liver enzyme, are a sign that the disease is causing liver damage. But even this marker is not a perfect predictor. Up to 30% of patients with liver damage have normal aminotranferase levels. A Look at Numbers A Look at Numbers When patients ask, "What will happen to me?", the best answer doctors can give is to explain how the disease progresses in an average group of patients. Of every 100 people infected with HPV: 75 to 85 can develop long-term infection; of the following: As these numbers show, most people infected with hepatitis develop chronic infections. Among them, most have some signs of liver damage. But the numbers are also reassuring. Less than 7% of those who have chronic hepatitis C die from virus complications. That means for a vast majority of people, the virus is not fatal. In many, it causes nothing but mild symptoms such as fatigue. The Changing Table of HCV Infection The Changing Table of HCV Infection There are more good news coming out of clinical trials and pharmaceutical laboratories. The combined treatment used today is more effective than anything doctors could offer when the disease arose in 1989. Combination therapy can eliminate the virus in about half of all patients. Some combination treatments can do even better. A 2007 study of nearly 1,000 patients with hepatitis C showed a 99 percent healing rate after peginterferon and ribavirin treatment, with a number of patients who were left free of disease for seven years. The prognosis for people infected with HCV is brighter than ever. And it is likely to be brighter as doctors learn more effective combinations of existing drugs and as new drugs develop. ReferencesYounossi ZM, McCullough AJ. Metabolic syndrome, non-alcoholic liver disease and hepatitis C virus: impact on disease progression and response to treatment. Liver International. 2009 Apr;29(4):617.American Medical Association. Healing rates becoming the norm for patients with hepatitis C. June 2007. http://www.ama-assn.org/amednews/2007/06/18/hlsc0618.htmThein HH, Yi Q, Dore GJ, Krahn MD. Estimates of progression rates of specific fibrosis in stages in the chronic infection of the hepatitis virus c: A meta-analysis and meta-regress. Hepatology. August 2008; 48(2): 418-431. Lauer, GL, et al. Hepatitis C virus infection, New England Journal of Medicine, July 5, 2001, pp 41-52Ho, W et al. Alcohol increases hepatitis C virus in human cells, Hepatology, July 2003, pp 57-65Pessione, F et al. Predictive factors of quinquennial survival in patients with excessive consumption of alcohol and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence, Liver International, Feb 2003, pp 45-53Seeff et al, The National Institutes of Health consensus Development Conference management of hepatitis C 2002, Clinical Liver Disease, Feb 2003, pp 261-87Cronic Hepatitis C: Disease Management, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). http://digestive.niddk.nih.gov/ddiseases/pubs/chronichepc/Thomas DL et al, The natural history of hepatitis C virus infection: host, viral and environmental factors, Journal of the American Medical Association, July 26, 2000, pp. 450-6Quaglio GL et al, Hepatitis Virus infection C: prevalence, predictive variables and prevention opportunities among drug users in Italy, Journal of Viral Hepatitis, Sep 2003, pp 394-400 Hisada et al., increase of hepatitis C viruses among injecting drug users infected with HIV and HTLV2, Journal of Infectious Diseases, September 15, 2003, pp 8 Thein HH, Yi Q, Dore GJ, Krahn MD. Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV on the age of antiretroviral therapy: a meta-analysis. AIDS. 1 October 2008; 22(15). Centers for Disease Control and Prevention. Hepatitis C Frequently asked questions. http://www.cdc.gov/hepatitis/C/cFAQ.htm Copyright © 2020 HealthDay. All rights reserved. This site meets the HONcode standard for reliable health Wellness A-ZHealthDayConsumer Health News Professional News

Survival of patients with HCV cirrhosis and sustained virologic response is similar to the general population.... Treated hepatitis C virus (HCV) cirrhotic patients can have normal life expectancy

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